Merkel cell carcinoma: If no breslow, then what?

Merkel cell carcinoma: if no breslow, then what?

Merkel cell carcinoma (MCC) is a skin tumor of neuroendocrine origin with a mortality of 33%, the highest of any cutaneous malignancy. Within the United States the estimated annual incidence is increasing and is estimated at 0.44 per 100,000 persons, resulting in roughly 1,000 new cases per year [1]. Several factors may be contributing to this trend, including changes in the major risk factors ...

If Not Turing's Test, Then What?

ence, then it will be worthwhile to identify good problems, and even more worthwhile to discover the attributes that make them good problems. This discovery process is necessarily empirical, so we examine several challenge problems, beginning with Turing’s famous test, and more than a dozen attributes that challenge problems might have. We are led to a contrast between research strategies—the s...

Too many pedodontists? If so, what then?

Digital Merkel cell carcinoma.

Merkel cell carcinoma (MCC) is a rare and biologically aggressive neuroendocrine tumour of the skin. Recent analysis of a surveillance, epidemiology and end results program has shown a statistically significant increase of 8% per year in the age-adjusted rates for MCC of the skin over the past 15 years. MCC commonly presents as a painless, rapidly growing, single red or purple cutaneous nodule....

Merkel cell carcinoma

BACKGROUND Merkel cell carcinoma (MCC) is an unusual primary neuroendocrine carcinoma of the skin. MCC is a fatal disease, and patients have a poor chance of survival. Moreover, MCC lacks distinguishing clinical features, and thus by the time the diagnosis is made, the tumour usually have metastasized. MCC mainly affects sun-exposed areas of elderly persons. Half of the tumours are located in t...